Ibisabwa mu kwirinda no mu mikorere ya Gelatin mu tubyimba duto kandi tworoshye

Nk'igikoresho cy'ingenzi gitunganya filime cyakozwe mu buryo bukomeye kandi kapsule yoroshyes, gelatin isaba kugenzura neza ubuziranenge n'imikorere kugira ngo habeho ihindagurika rya kapsule n'umutekano w'imiti.

Amabwiriza yo Kwitondera Gukoresha

1. Kugenzura isuku: Hitamo gelatin yo mu rwego rw'imiti kugira ngo wirinde ibyuma biremereye cyane (urugero, lisansi, mercure) na mikorobe, wirinde kwangirika kwa capsule cyangwa ibyago by'umutekano.
2. Gucunga ubushuhe: Gelatin ni nziza cyane. Ubushuhe bwo kubika bugomba kuguma kuri 45%-65% kugira ngo hirindwe koroha, gufatana, kwangirika cyangwa kwangirika. Ubushuhe bwo mu iduka mu gihe cyo gukora nabwo bugomba kugenzurwa kugira ngo harebwe ko ifu imeze neza.
3. Guhuza n'Ibikubiyemo: Kora ibizamini byo guhuza ibintu mbere y'igihe. Aside ikomeye, alkali, cyangwa ibice bigabanya ogisijeni mu biyigize bishobora kwangiza imiterere ya gelatin.

Ibisabwa mu mikorere

• Kapsule zikomeye: Genzura neza ingano y'umuti wa gelatin (ubusanzwe 12%-15%) n'ubushyuhe (50-60℃) kugira ngo urebe ko nta tubuto dusa, ukomeze kugira ubunini bw'igishishwa cya capsule (ubusanzwe 0.15-0.25mm). Kumutsa amasaha 24-48 nyuma yo gutegurwa, ubushuhe bwa nyuma bugahagarara kuri 12%-16%.
• Udupira tworoshye: Shyiramo pulasitiki (urugero, glycerol) mu gipimo cya gelatin:glycerol = 1:0.3-0.5 kugira ngo wongere ubushobozi bwo koroshya. Genzura ubushyuhe bwo gushyuha kuri 20-30℃ kugira ngo wirinde kwangirika. Shyira amazi mu masaha 48-72, ubushuhe bugumane kuri 12%-16% kugira ngo ububiko bukomeze.

Hari itandukaniro rinini mu bwoko bwa gelatin, imiterere, n'ibisabwa mu bwiza hagati y'ibiryo byoroshye na kapsule ikomeyes, bikomoka ku buryo butandukanye bwo gukora ndetse n'ibyo bakeneye mu buryo bufatika.

1. Itandukaniro mu bwoko bwa Gelatin

Nubwo imiterere ya gelatin isa n'iya shimi, imiterere y'imiterere yayo—iterwa n'ibikoresho fatizo n'uburyo itunganywa—ituma ikwiriye ubwoko butandukanye bwa kapsule.

• Kapsule zikomeye: Shyira imbere "ubukomere" n' "ubudahinduka". Gelatin y'amagufwa ikoreshwa cyane kubera imbaraga zayo nyinshi za gel.
• Udupira tworoshye: Shyira imbere "ubukonje" n' "ubushobozi bwo gukora filime". Gelatin y'uruhu (urugero, uruhu rw'inka, gelatin y'uruhu rw'ingurube) ihura n'ibikenewe mu nganda ifite ubukonje n'ubudahangarwa bukwiye, bigabanya kwangirika cyangwa gucikagurika.

1. Itandukaniro mu bipimo bya Gelatin

Ibipimo by'ingenzi (imbaraga za gel, ubushyuhe, ubushuhe) bigira ingaruka ku buryo ibintu bihinduka:

1. Gelatin yo gukoresha mu tubyimba duto

• Imbaraga za Jeli: Igipimo cy'ingenzi, gisaba ≥220 Indabyo g. Ingufu nyinshi za jeli zituma ikomera neza kandi zigakomeza kurwanya ingaruka, bikarinda kwangirika.
• Ubucucike: Igenzurwa kuri 25-40 mPa・s (kuri 60℃). Ubushyuhe buringaniye bwirinda ko ibikonoshwa bito kandi byoroshye kwangirika (hasi cyane) cyangwa kugabanya ubushobozi bwo gushushanya (hejuru cyane).
• Ubushuhe: ≤12%. Ubushuhe bwinshi butera koroha/gufatana; ubushuhe budahagije butuma habaho gucika intege.

2. Gelatin yo Udupira tworoshye

• Imbaraga za Jeli: Ikenewe nke, ubusanzwe ≥180 Indabyo g. Ubukana bwinshi ntabwo ari ngombwa; ubukana ni bwo bushyirwa imbere—imbaraga nyinshi za gel zituma ibishishwa bikomeye kandi byoroshye kwangirika.
• Ubucucike: Ibikenewe cyane, 40-60 mPa・s (kuri 60℃). Ubushyuhe bwinshi butuma filime ikora neza kandi ikagumana imiterere nyuma yo kuyitunganya.
• Ubushuhe: ≤13%. Ireshya gato ugereranyije na capsule zikomeye kugira ngo ikomeze kuba ingirakamaro kandi irinde ko yumuka.

1. Ibisabwa mu buziranenge rusange (Amahame ngenderwaho ya farumasi)

Ubwoko bwombi bwa capsule busaba gelatin yo mu rwego rw'imiti yujuje ibi bikurikira by'umutekano n'ikoreshwa:

1. Ubwiza: Nta byuma biremereye byinshi (urugero, icyuma cy'ubutare ≤0.1 mg/kg, arsenic ≤0.05 mg/kg), mikorobe (yubahiriza amahame ntarengwa yo kutandura/mikorobe, urugero, nta Escherichia coli yabonetse), n'imyanda yangiza.
2. Umucyo n'Ibara: Nta ibara cyangwa umuhondo werurutse, nta guhindagurika ku buryo bugaragara cyangwa ibintu bidasanzwe, bituma isura yera kandi isa neza.
3. Agaciro ka pH: 5.5-7.5 (hafi ya neutral) kugira ngo hirindwe aside-base reactions hamwe n'ibirimo, birinda ubudahinduka bw'imiti.
4. Ibirimo ivu: ≤2.0%, bigaragaza ubuziranenge—ivu ryinshi rigaragaza umwanda udakomoka ku bimera.
5. Gushonga: Irabyimba kandi igashonga buhoro buhoro mu mazi, igashonga vuba mu mazi yo mu gifu kugira ngo irebe ko ibikubiye mu gifu bisohora neza.