Gargaɗi da Bukatun Tsarin Aiki don Gelatin a cikin Kapsul Masu Tauri da Taushi

A matsayin babban kayan samar da fim na tauri da ƙapsule mai laushis, gelatin yana buƙatar ingantaccen inganci da kuma kula da tsari don tabbatar da kwanciyar hankali na capsules da amincin magani.

Gargaɗi don Amfani

1. Sarrafa Tsarkaka: Zaɓi gelatin mai darajar magunguna don guje wa ƙarfe masu nauyi (misali, gubar, mercury) da ƙananan halittu, don hana lalacewar ƙwayoyin cuta ko haɗarin aminci.
2. Gudanar da Danshi: Gelatin yana da tsafta sosai. Ya kamata a kiyaye danshi a yanayin ajiya a kashi 45%-65% domin gujewa laushin capsules, mannewa, karyewa, ko fashewa. Danshin wurin aiki yayin samarwa shima yana buƙatar kulawa don tabbatar da ingancin ƙira.
3. Daidaituwa da Abubuwan da ke ciki: Yi gwaje-gwajen dacewa da juna a gaba. Abubuwan acid masu ƙarfi, alkalis, ko abubuwan da ke haifar da iskar shaka a cikin abubuwan da ke ciki na iya lalata tsarin gelatin.

Bukatun Tsarin

• Kapsul Mai Tauri: Daidaita yawan ruwan gelatin (yawanci 12%-15%) da zafin jiki (50-60℃) don tabbatar da daidaito ba tare da kumfa ba, tare da kiyaye kauri mai daidaito na harsashi (galibi 0.15-0.25mm). Busar da shi na tsawon awanni 24-48 bayan ƙera shi, tare da danshi na ƙarshe ya daidaita a 12%-16%.
• Kapsul Masu Taushi: A ƙara masu tacewa (misali, glycerol) zuwa ruwan gelatin a rabon gelatin:glycerol = 1:0.3-0.5 don haɓaka sassauci. A kula da zafin pelleting a 20-30℃ don hana lalacewa. A busar na tsawon awanni 48-72, tare da kiyaye danshi a 12%-16% don kwanciyar hankali a ajiya.

Akwai bambance-bambance masu mahimmanci a cikin nau'in gelatin, ƙayyadaddun bayanai, da buƙatun inganci tsakanin laushi da kapsul mai tauris, wanda ya samo asali ne daga tsarin kera su daban-daban da kuma buƙatun siffar jiki.

1. Bambance-bambance a cikin Nau'in Gelatin

Duk da cewa yana da kama da sinadarai iri ɗaya, halayen gelatin na zahiri—wanda aka ƙayyade ta hanyar tushen kayan aiki da sarrafawa—sun sa ya dace da nau'ikan capsules daban-daban.

• Kapsul Mai Tauri: A fifita "tauri" da "kwanciyar hankali". Ana amfani da gelatin na ƙashi sosai saboda ƙarfin gel ɗinsa mai girma.
• Kapsul Masu Taushi: A ba da fifiko ga "lalacewa" da "ikon ƙirƙirar fim". Gelatin na fata (misali, fatar shanu, gelatin na fatar alade) yana biyan buƙatun masana'antu tare da ɗanko da laushi mai dacewa, yana rage lalacewa ko fashewa.

1. Bambance-bambance a cikin Bayanin Gelatin

Mahimman sigogi (ƙarfin gel, danko, danshi) suna shafar daidaitawar tsari kai tsaye:

1. Gelatin don capsules masu tauri

• Ƙarfin Gel: Alamar asali, tana buƙatar ≥220 Bloom g. Ƙarfin gel mai ƙarfi yana tabbatar da ingantaccen tauri da juriya ga tasiri, yana hana karyewa.
• Danko: Ana sarrafa shi a 25-40 mPa・s (a 60℃). Matsakaicin danko yana hana siririn harsashi mai rauni (ƙasa da yawa) ko raguwar ingancin ƙira (mai yawa).
• Danshi: ≤12%. Yawan danshi yana haifar da laushi/mannewa; rashin isasshen danshi yana haifar da karyewa.

2. Gelatin don gashi Kapsul Masu Taushi

• Ƙarfin Gel: Ƙananan buƙata, yawanci ≥180 Bloom g. Ba dole ba ne babban tauri; ana fifita sassauci—ƙarfin gel mai yawa yana haifar da harsashi mai tauri da karyewa.
• Danko: Bukatar da ake buƙata mafi girma, 40-60 mPa・s (a 60℃). Babban danko yana tabbatar da samuwar fim iri ɗaya da riƙe siffa bayan ƙera shi.
• Danshi: ≤13%. Ya ɗan fi ƙapsul mai tauri girma don kiyaye laushi da hana bushewar fata.

1. Bukatun Inganci na gama gari (Ka'idojin Magunguna)

Duk nau'ikan capsules suna buƙatar gelatin mai inganci wanda ya dace da waɗannan sharuɗɗan aminci da amfani:

1. Tsarkaka: Ba shi da ƙarfe mai nauyi da yawa (misali, gubar ≤0.1 mg/kg, arsenic ≤0.05 mg/kg), ƙwayoyin cuta (masu bin ƙa'idodin iyakancewar rashin haihuwa/ƙwayoyin cuta, misali, ba a gano Escherichia coli ba), da kuma ƙazanta masu cutarwa.
2. Bayyanar da Launi: Ba shi da launi ko rawaya mai haske, ba tare da wata datti ko wani abu na waje ba, yana tabbatar da tsabta da kamanni iri ɗaya.
3. Darajar pH: 5.5-7.5 (kusan tsaka tsaki) don guje wa halayen acid-base tare da abun ciki, yana kare lafiyar magani.
4. Abubuwan da ke cikin Toka: ≤2.0%, yana nuna tsarki—toka mai yawa yana nuna gurɓataccen ƙazanta mara tsari.
5. Narkewa: Yana kumbura kuma yana narkewa a hankali a cikin ruwa, yana narkewa da sauri a cikin ruwan ciki don tabbatar da cewa abun cikin yana fitar da inganci.