Cov Txheej Txheem Zoo ntawm Pharmacopoeial rau cov tshuaj - qib Gelatin

Tshuaj - qib gelatin (Cov tshuaj Gelatin) tau los ntawm kev hydrolyzing cov tawv tsiaj xws li cov tawv nyuj. Nws yog ib qho tshuaj siv ntau, siv dav hauv kev lag luam tshuajrau Cov plhaub capsule, cov tshuaj pleev xim rau cov tshuaj granules, thiab cov tshuaj stabilizers, thiab lwm yam. Cov tshuaj gelatin qib tshuaj yuav tsum ua tau raws li cov qauv zoo nruj kom ntseeg tau tias nws muaj kev nyab xeeb thiab ua haujlwm tau zoo thaum siv rau hauv cov tshuaj. Cov hauv qab no yog cov qauv zoo rau cov tshuaj gelatin qib tshuaj raws liCov Tshuaj Kho Mob Suav:

1. Cov tsos thiab cov khoom

Tshuaj - qib gelatin yog ib yam khoom daj los yog daj me ntsis, pob tshab mus rau pob tshab me ntsis zoo li jelly los yog cov khoom siv granular nrog ib qho ci ntsa iab tshwj xeeb. Cov khoom yuav tsum tsis txhob muaj cov khoom txawv teb chaws pom tseeb lossis cov khoom tsis huv, thiab nws yuav tsum tsis txhob muaj ntxhiab tsw phem. Qhov huv thiab pob tshab ntawm qhov tsos yog ib qho ntawm cov cim tseem ceeb ntawm kev tswj xyuas zoo, uas cuam tshuam rau nws txoj kev siv rau hauv cov tshuaj.

2.Kev yaj tau

Cov gelatin qib tshuaj tuaj yeem yaj tag nrho hauv dej sov kom ua tau cov kua pob tshab thiab khov. Qhov solubility ntawm gelatin txiav txim siab nws cov kev ua tau zoo hauv cov plhaub capsule thiab lwm yam tshuaj. Solubility zoo pab txhim kho cov tshuaj tso tawm.

3. Cov ntsiab lus sib xyaw ua ke ntawm cov tshuaj gelatin

Lub ntsiab lus coagulation ntawm gelatin yog ib qho ntawm cov cim qhia tseem ceeb los ntsuas nws qhov zoo, thiab nws feem ntau yuav tsum nyob nruab nrab ntawm 35 ° C thiab 38 ° C. Kev tswj hwm ntawm qhov taw tes coagulation yog qhov tseem ceeb rau kev ruaj khov thiab kev siv cov tshuaj, tshwj xeeb tshaj yog nyob rau hauv ib puag ncig nrog kev hloov pauv kub loj.

4. Cov ntsiab lus noo noo

Feem ntau cov dej noo ntawm cov tshuaj gelatin yuav tsum nyob nruab nrab ntawm 10% thiab 15%. Cov dej noo ntau dhau lossis tsawg dhau yuav cuam tshuam rau kev ruaj khov ntawm gelatin thiab nws cov txiaj ntsig siv hauv tshuaj. Cov dej noo ntau dhau yuav ua rau gelatin puas tsuaj lossis puas tsuaj zoo, thaum cov dej noo tsis txaus yuav cuam tshuam rau nws qhov yooj ywm thiab kev ua haujlwm.

5. Cov ntsiab lus tshauv

Feem ntau cov tshauv hauv gelatin yuav tsum tsis pub tshaj 2% (xam rau qhov qhuav). Cov tshauv ntau dhau yuav qhia tau tias cov gelatin muaj cov tshuaj tsis huv, uas cuam tshuam rau nws qhov zoo. Kev tswj cov tshauv yog qhov tseem ceeb kom ntseeg tau tias cov gelatin huv thiab tsis muaj kuab paug.

6. Kev Txwv ntawm Cov Kab Mob

Ua ib qho tshuaj ntxiv rau kev siv tshuaj, cov tshuaj gelatin uas siv rau kev kho mob yuav tsum ua tau raws li cov kev cai txwv tsis pub muaj kab mob me me. Cov ntawv sau tshuaj qhia txog nws cov kev txwv tsis pub muaj kab mob me me, thiab cov khoom gelatin yuav tsum tsis txhob muaj cov kab mob me me uas ua rau muaj kev phom sij kom ntseeg tau tias lawv yuav tsis cuam tshuam rau kev nyab xeeb ntawm cov tshuaj.

7. Cov Ntsiab Lus Chloride

Raws li ib qho ntawm cov qauv zoo tseem ceeb, cov chloride hauv cov tshuaj gelatin qib tshuaj yuav tsum tsis pub tshaj 0.05%. Cov chloride ntau dhau yuav muaj kev cuam tshuam tsis zoo rau kev ruaj khov thiab kev siv tau ntawm cov tshuaj.