Miyezo Yabwino ya Pharmacopoeial ya Gelatin ya Mankhwala - kalasi

Mankhwala - kalasi gelatin (Gelatin ya Mankhwala() imapezeka pothira madzi m'zikopa za nyama monga chikopa cha ng'ombe. Ndi chinthu chogwiritsidwa ntchito kwambiri pa mankhwala, chomwe chimagwiritsidwa ntchito kwambiri mu makampani opanga mankhwalachifukwa cha Zipolopolo za Kapisozi, zophimba za granules za mankhwala, ndi zokhazikika za mankhwala, ndi zina zotero. Gelatin ya mtundu wa mankhwala iyenera kukwaniritsa miyezo yokhwima ya khalidwe kuti iwonetsetse kuti ndi yotetezeka komanso yogwira ntchito ikagwiritsidwa ntchito mu mankhwala. Izi ndi zofunikira pamlingo wa khalidwe la gelatin ya mtundu wa mankhwala malinga ndiMankhwala a ku China:

1. Mawonekedwe ndi Katundu

Mankhwala - kalasi gelatin ndi yachikasu kapena yachikasu yopepuka, yowonekera pang'ono mpaka yowonekera pang'ono ngati jelly kapena zinthu zopyapyala zokhala ndi kuwala kwina. Chogulitsacho sichiyenera kukhala ndi zinthu zakunja kapena zodetsa, komanso sichiyenera kukhala ndi fungo losasangalatsa. Ukhondo ndi kuwonekera bwino kwa mawonekedwe ndi chimodzi mwa zizindikiro zofunika kwambiri zowongolera khalidwe, zomwe zimakhudza kugwiritsidwa ntchito kwake mu mankhwala.

2.Kusungunuka

Gelatin yopangidwa ndi mankhwala imatha kusungunuka kwathunthu m'madzi ofunda kuti ipange yankho lowonekera komanso lokhuthala. Kusungunuka kwa gelatin kumatsimikizira momwe imagwirira ntchito m'mabokosi a capsule ndi mankhwala ena. Kusungunuka bwino kumathandiza kuti mankhwala atuluke bwino.

3. Malo Olumikizira Gelatin

Malo oundana a gelatin ndi chimodzi mwa zizindikiro zofunika kwambiri poyesa ubwino wake, ndipo nthawi zambiri amafunika kukhala pakati pa 35°C ndi 38°C. Kulamulira malo oundana n'kofunika kwambiri kuti mankhwala azikhala olimba komanso ogwiritsidwa ntchito bwino, makamaka m'malo omwe kutentha kumasinthasintha kwambiri.

4. Chinyezi Chokwanira

Chinyezi cha gelatin ya mankhwala nthawi zambiri chimayenera kukhala pakati pa 10% ndi 15%. Chinyezi chochuluka kapena chochepa kwambiri chingakhudze kukhazikika kwa gelatin ndi momwe imagwiritsidwira ntchito m'mankhwala. Chinyezi chochuluka chingayambitse kuwonongeka kapena kuchepa kwa khalidwe la gelatin, pomwe chinyezi chosakwanira chingakhudze kusinthasintha kwake ndi magwiridwe antchito ake.

5. Zamkati mwa Phulusa

Phulusa la gelatin nthawi zambiri limafunika kuti lisapitirire 2% (kuwerengedwa mouma). Phulusa lochuluka kwambiri likhoza kusonyeza kuti gelatin ili ndi zinthu zodetsedwa, zomwe zimakhudza ubwino wake. Kulamulira kuchuluka kwa phulusa ndikofunikira kuti gelatin ikhale yoyera komanso yopanda kuipitsidwa.

6. Malire a Tizilombo toyambitsa matenda

Monga chowonjezera mankhwala, gelatin yamtundu wa mankhwala iyenera kukwaniritsa zofunikira zokhwima za ma microbes. Pharmacopoeia imatchula malire ake a ma microbes, ndipo zinthu za gelatin siziyenera kukhala ndi ma microbes oopsa kuti zitsimikizire kuti sizikhudza chitetezo cha mankhwala.

7. Kuchuluka kwa Chloride

Monga imodzi mwa miyezo yofunika kwambiri ya khalidwe, kuchuluka kwa kloridi mu gelatin ya mankhwala sikuyenera kupitirira 0.05%. Kloridi wochuluka ukhoza kusokoneza kukhazikika ndi kupezeka kwa mankhwala.